WALDENSTROM

Waldenstrom macroglobulinemia is a syndrome of IgM hypergammaglobulinemia that occurs in the setting of a low grade non-Hodgkin lymphoma characterized by B cells that are morphologically a hybrid of lymphocytes and plasma cells. These cells secrete the IgM paraprotein, and many clinical manifestations of the disease are related to this macroglobulin. Patients usually present with […]